NAD+ (100mg / 250mg / 750mg) Research Material

Product Introduction

NAD+ (100mg / 250mg / 750mg) is a research-grade nicotinamide adenine dinucleotide material supplied by Core Peptides for laboratory and scientific research applications. NAD+, short for nicotinamide adenine dinucleotide, is a naturally occurring coenzyme involved in fundamental cellular biochemical processes and has been extensively studied in molecular and cellular biology.

Available in 100mg, 250mg, and 750mg quantities, this NAD+ research material provides laboratories with flexible options for controlled experimental work. Each option is supplied with an emphasis on quality, consistency, and appropriate research use. NAD+ (100mg / 250mg / 750mg) is intended exclusively for laboratory research and is not intended for human or veterinary use.

What Is NAD+?

NAD+ is a coenzyme found throughout living cells and plays an important role in numerous biochemical reactions. It participates in oxidation-reduction reactions, helping facilitate the transfer of electrons during cellular metabolic processes.

Because of its central role in cellular biochemistry, NAD+ has become an important subject of research across fields including cellular biology, biochemistry, metabolism, mitochondrial research, and molecular biology.

Researchers can use NAD+ as a defined research material when studying biochemical pathways, enzyme activity, cellular metabolism, and related molecular mechanisms.

NAD+ Research Applications

NAD+ is widely studied in laboratory research because of its involvement in cellular energy metabolism and redox biology. Research applications may include investigations into enzyme activity, metabolic pathways, mitochondrial function, cellular signaling, and biochemical reactions.

Laboratory studies can examine the role of NAD+ in different experimental systems, including biochemical assays and cellular research models. Researchers may also investigate interactions between NAD+ and enzymes involved in cellular metabolism.

The appropriate experimental concentration, assay conditions, controls, and methodology should be established by qualified researchers according to the objectives of their individual research projects.

Available Quantities

Core Peptides offers NAD+ in three research quantities:

• 100mg — a smaller quantity for laboratory experiments and analytical research.
• 250mg — a mid-range quantity for research projects requiring additional material.
• 750mg — a larger quantity suitable for experiments requiring greater amounts of research material.

All available options contain NAD+ and are supplied exclusively for laboratory and scientific research.

Product Specifications

Quality and Consistency

Consistent research materials are important for reproducible laboratory experiments. NAD+ (100mg / 250mg / 750mg) is supplied with a focus on quality and consistency for controlled scientific research.

Researchers should review available product and batch documentation when evaluating NAD+ for a specific experimental application. Appropriate analytical methods and laboratory controls should be used when assessing the material in an experimental system.

Packaging and Handling

NAD+ is securely packaged to help protect the research material during storage and transportation. Researchers should follow the applicable product documentation and established laboratory procedures for receiving, handling, storage, and preparation.

Because research materials can have specific handling requirements, laboratories should use appropriate procedures and conditions based on the product documentation and their own validated protocols.

Why Choose Core Peptides?

Core Peptides provides research-oriented materials for laboratories, researchers, and scientific investigations. With NAD+ (100mg / 250mg / 750mg), researchers can select a quantity that fits their particular laboratory requirements.

Clear product identification, quantity information, research-use positioning, and secure packaging make NAD+ a practical research material for laboratories investigating cellular and biochemical processes.

Research Use Disclaimer

NAD+ (100mg / 250mg / 750mg) is supplied strictly for laboratory and scientific research purposes. It is not approved or intended for human consumption, self-administration, diagnosis, treatment, prevention, or mitigation of any disease or medical condition. It is not intended for veterinary use. Researchers are responsible for complying with applicable laws, institutional requirements, laboratory safety standards, and appropriate handling procedures.

Product Features

• Available in 100mg, 250mg, and 750mg
• Contains NAD+ (nicotinamide adenine dinucleotide)
• Research-grade laboratory material
• Suitable for biochemical and molecular research
• Relevant to cellular metabolism and redox research
• Quality-focused production
• Secure packaging
• For research use only
• Not for human or veterinary use

References:

1. Schultz, Michael B, and David A Sinclair. “Why NAD(+) Declines during Aging: It’s Destroyed.” Cell metabolism vol. 23,6 (2016): 965-966. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088772/
2. Braidy N, Liu Y. NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. Exp Gerontol. 2020 Apr;132:110831. doi: 10.1016/j.exger.2020.110831. https://pubmed.ncbi.nlm.nih.gov/31917996/
3. Johnson, Sean, and Shin-Ichiro Imai. “NAD + biosynthesis, aging, and disease.” F1000Research vol. 7 132. 1 Feb 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795269/
4. Bieganowski P, Brenner C. Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell. 2004 May 14;117(4):495-502. https://pubmed.ncbi.nlm.nih.gov/15137942/
5. Fang, E. F., Lautrup, S., Hou, Y., Demarest, T. G., Croteau, D. L., Mattson, M. P., & Bohr, V. A. (2017). NAD+ in Aging: Molecular Mechanisms and Translational Implications. Trends in molecular medicine, 23(10), 899–916. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494058/
6. Harden, A; Young, WJ (24 October 1906). “The alcoholic ferment of yeast-juice Part II.–The coferment of yeast-juice”. Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character. 78 (526): 369–375. https://royalsocietypublishing.org/doi/10.1098/rspb.1906.0070
7. Mills KF, Yoshida S, Stein LR, Grozio A, Kubota S, Sasaki Y, Redpath P, Migaud ME, Apte RS, Uchida K, Yoshino J, Imai SI. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016 Dec 13;24(6):795-806. https://pubmed.ncbi.nlm.nih.gov/28068222/
8. Long AN, Owens K, Schlappal AE, Kristian T, Fishman PS, Schuh RA. Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model. BMC Neurol. 2015 Mar 1;15:19. https://pubmed.ncbi.nlm.nih.gov/25884176/
9. Safety & Efficacy of Nicotinamide Riboside Supplementation for Improving Physiological Function in Middle-Aged and Older Adults. https://clinicaltrials.gov/ct2/show/NCT02921659
10. Braidy N, Liu Y. NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. Exp Gerontol. 2020 Apr;132:110831. https://pubmed.ncbi.nlm.nih.gov/31917996/
11. Wang S, Xing Z, Vosler PS, Yin H, Li W, Zhang F, Signore AP, Stetler RA, Gao Y, Chen J. Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair. Stroke. 2008 Sep;39(9):2587-95. https://pubmed.ncbi.nlm.nih.gov/18617666/
12. Rajman, Luis et al. “Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence.” Cell metabolism vol. 27,3 (2018): 529-547. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342515/
13. Heer C, et al, Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity. Journal of Biological Chemistry. Volume 295, Issue 52, Dec 2020. https://www.jbc.org/article/S0021-9258(17)50676-6/fulltext
14. Mehmel, Mario et al. “Nicotinamide Riboside-The Current State of Research and Therapeutic Uses.” Nutrients vol. 12,6 1616. 31 May. 2020, doi:10.3390/nu12061616 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352172/
15. Leung A, Todorova T, Ando Y, Chang P. Poly(ADP-ribose) regulates post-transcriptional gene regulation in the cytoplasm. RNA Biol. 2012 May;9(5):542-8. doi: 10.4161/rna.19899. Epub 2012 May 1. PMID: 22531498; PMCID: PMC3495734.
16. Croteau DL, Fang EF, Nilsen H, Bohr VA. NAD⁺ in DNA repair and mitochondrial maintenance. Cell Cycle. 2017 Mar 19;16(6):491-492. doi: 10.1080/15384101.2017.1285631. Epub 2017 Feb 1. PMID: 28145802; PMCID: PMC5384578.